Denu Lab
at the Wisconsin Institute for Discovery

Margie Borra-Garske

Position title: Biomolecular Chemistry Graduate Student

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Selected Publications

Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. Borra MT, O’Neill FJ, Marshall B, Verdin E, Foltz KR, Denu JM. JBC 2002.

Quantitative assays for characterization of the Sir2 family of NAD(+)-dependent deacetylases. Borra MT and Denu JM. Methods Enzymol. 2003.

Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases. Borra MT, Langer MR, Slama JT, Denu JM. Biochemistry 2004.

Mechanism of human SIRT1 activation by resveratrol. Borra MT, Smith BC, Denu JM. JBC 2005.