Vyacheslav (Slava) Kuznetsov, PhD

Selected Publications

Potent Activation of NAD ⁺-Dependent Deacetylase Sirt7 by Nucleosome Binding. Kuznetsov VI, Liu WH, Klein MA, and Denu JM. ACS Chem Biol. 2022.

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6. Liu WH, Zheng J, Feldman JL, Klein MA, Kuznetsov VI, Peterson CL, Griffin PR, Denu JM.  Nat Commun 2020.

Mechanism of Activation for the Sirtuin 6 Protein Deacylase. Klein MA, Lie C, Kuznetsov VI, Feltenberger JB, Tang W, Denu JM. J Biol Chem 2020.

General method for rapid purification of native chromatin fragments. Kuznetsov VI, Haws SH, Fox CA, Denu JM. J Biol Chem 2018.