Wallace Liu

Education

B.S., Biochemistry and Cell Biology, UC San Diego

Ph.D., Pharmacology, University of Colorado Anschutz Medical Campus

Publications

Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1. Liu WH, Miner RE, Albaugh BN, Ananiev GE, Wildman SA, Denu JM. Biochemistry 2022.

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6. Liu WH, Zheng J, Feldman JL, Klein MA, Kuznetsov VI, Peterson CL, Griffin PR, Denu JM.  Nat Commun 2020.

Methyl-Metabolite Depletion Elicits Adaptive Responses to Support Heterochromatin Stability and Epigenetic Persistence. Haws SA, Yu D, Ye C, Wille CK, Nguyen LC, Krautkramer KA, Tomasiewicz JL, Yang SE, Miller BR, Liu WH, Igarashi K, Sridharan R, Tu BP, Cryns VL, Lamming DW, Denu JM. Mol Cell 2020.