Position title: Graduate Student, CMB
B.S., Biological Science, Peking University, 2006-2010
National Undergraduate Innovation Research Fellowship, 2008-2009
Peking University SK Scholarship, 2006-2007
Zhangli has been interested in chromatin biology and epigenetics for years. She started in research focused on chromatin-remodeler PKL in Arabidopsis, at Peking-Yale Joint Center under supervision of Prof. Liumin Fan. She then came to the states and did thesis project about yeast telomerase in Prof. Peter Baumann’s lab at Stowers Institute for Medical Research. In her free time, Zhangli enjoys cooking and photography.
Histone modification is a major component of epigenetic regulation, however its complexity and intricacy of recognition have not been revealed until recently. Zhangli’s interest is to identify novel patterns of combinatorial histone modifications and their biological meanings. Current projects include identifying combinatorial histone modifications representing specific chromatin states and characterizing histone binding properties of chromatin-binding proteins.
Reading the Combinatorial Histone Language. Su Z and Denu JM. ACS Chem Biol. 2016.
MARCC (Matrix-Assisted Reader Chromatin Capture): An Antibody-Free Method to Enrich and Analyze Combinatorial Nucleosome Modifications. Su Z and Denu JM. Current Protocols in Molecular Biology 2015.
ChIP-less analysis of chromatin states. Su Z, Boersma MD, Lee J, Oliver SS, Liu S, Garcia BA and Denu JM. Epigenetics & Chromatin 2014.
Other research experience
Stowers Institute for Medical Research, Research Advisor: Peter Baumann, 2009-2010
Peking-Yale Joint Research Center for Plant Molecular Genetics and Agro-Biotechnology, Research Advisor: Liu-min Fan, 2008-2009